Which analgesic is preferred for a patient taking glucocorticoids for pain management?

• A. Aspirin
• B. Acetaminophen
• C. Ibuprofen
• D. Naproxen

Answer: (B)

When a patient is taking glucocorticoids, nonsteroidal anti-inflammatory drugs raise the risk of stomach ulcers and GI bleeding, and this risk is amplified by steroids. Acetaminophen provides analgesia without the GI irritation associated with NSAIDs, so it is the safer initial choice for pain management in this scenario.

Keep in mind acetaminophen carries liver toxicity risk with high doses or alcohol use, so stay within recommended limits (and monitor liver function if use is chronic). If pain persists beyond acetaminophen's effect, management should be reassessed with caution and appropriate alternatives under supervision.